姓名：曹昊
性别：男
籍貫：遼甯丹東
聯系電話：13022410815
E-Mail：caohao2008@163.com
個人主頁：
職稱/職務：副教授
通訊☯⚜☯：遼甯省沈陽市沈河區文化路103号bevictor伟德
郵政編碼：110016
學習/工作經曆：
2014.8-至今 bevictor伟德 bevictor伟德 講師
2017.9-2019-9 清華大學 醫學院 博士後
2008.8-2013.12 吉林大學 生命科學學院 博士
2004.9-2008.6 重慶郵電大學 生物信息學院 學士
研究方向：
蛋白質的結構與功能
兼職情況：
科研/獲獎情況：
教學/指導研究生情況：
發表論文/出版著作：
（1）Characterization of nuclear localization signal in the N terminus of integrin-linked kinase-associated phosphatase (ILKAP) and its essential role in the down-regulationof RSK2 protein signaling. J Biol Chem. 2013 Mar 1; 288(9):6259-71.（co-first author）
（2）TGF-β2-induced ANGPTL4 expression promotes tumor progression and osteoclast differentiation in giant cell tumor of bone. Oncotarget. 2017 Jun 27;8(33):54966-54977.（co-first author）
（3）Trp358 is a key residue for the multiple catalytic activities of multifunctional amylase OPMA-N from Bacillus sp. ZW2531-1. Appl Microbiol Biotechnol. 2014 Mar;98(5):2101-11. （first author）
（4）Module recombination and functional integration of oligosaccharide-producing multifunctional amylase. Journal of Molecular Catalysis B: Enzymatic，2016.11.1，133：196~202 ; （first author）
（5）The second conserved motif in bacterial laccase regulates catalysis and robustnessJin Lanna; Yang Xue; Sheng Yongjie;Cao Hao; Ni Aixin; Zhang Yingjiu(*)Applied Microbiology and Biotechnology, 2018.5, 102(9): 4039~4048 ;
（6）The influence of two functional genetic variants of GRK5 on tau phosphorylation and their association with Alzheimer's disease risk.Zhang Y, Zhao J, Yin M, Cai Y, Liu S, Wang Y, Zhang X,Cao H,Chen T, Huang P, Mai H, Liu Z, Tao H, Zhao B, Cui L.Oncotarget. 2017 Aug 16;8(42):72714-72726.
（7）A Novel, Multi-Target Natural Drug Candidate, Matrine, Improves Cognitive Deficits in Alzheimer's Disease Transgenic Mice by Inhibiting Aβ Aggregation and Blocking the RAGE/Aβ Axis.Cui L, Cai Y, Cheng W, Liu G, Zhao J,Cao H, Tao H, Wang Y, Yin M, Liu T, Liu Y, Huang P, Liu Z, Li K, Zhao B.Mol Neurobiol. 2017 Apr;54(3):1939-1952.
（8）Ferulic acid inhibits the transition of amyloid-β42 monomers to oligomers but accelerates the transition from oligomers to fibrils.Cui L, Zhang Y,Cao H, Wang Y, Teng T, Ma G, Li Y, Li K, Zhang Y.J Alzheimers Dis. 2013;37(1):19-28
（9）Functional characterization of a special thermophilic multifunctional amylase OPMA-N and its N-terminal domain.Li F, Zhu X, Li Y,Cao H, Zhang Y.
Acta Biochim Biophys Sin (Shanghai). 2011 Apr;43(4):324-34.
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