姓名:紀雪飛
性别:女
籍貫:沈陽
聯系電話:18240208628
E-Mail:jixuefei2001@163.com
個人主頁:
職稱/職務:講師
通訊☯⚜☯:沈河區文藝路地王國際花園
郵政編碼:110010
學習/工作經曆:
2009/12月-至今,bevictor伟德,bevictor伟德, 講師
2006/08-2009/11,bevictor伟德,bevictor伟德,助教
2008/09-2014/06,bevictor伟德,bevictor伟德,博士
2003/09-2006/06,bevictor伟德,bevictor伟德,碩士
1999/09-2003/06,bevictor伟德,藥學院,本科
研究方向:
神經精神藥理:
AD發病機制及抗-AD藥物研究;
Sig-1受體與神經退行性疾病的相關研究
兼職情況:
科研/獲獎情況:
國家自然科學基金面上項目,81373992,一種新化合物——文冠果殼苷對APP/PS1轉基因小鼠突觸可塑性損傷的保護作用及機制研究,2014/01-2017/12,70萬元,申請結題,參加。
2. 遼甯省博士啟動基金,201601143,Sigma-1R對腦缺血再灌注導緻小鼠大腦内質網應激及細胞凋亡的影響,在研,5萬,主持。
教學/指導研究生情況:
承擔本科生理論課《藥理學》、《專業英語》的授課,
承擔《藥理學》《中藥藥理學》實驗課教學
發表論文/出版著作:
(1)Ji XF, Chi TY, Liu P, Li LY, Xu JK, Xu Q, Zou LB, Meng DL, The total triterpenoid saponins of Xanthoceras sorbifolia improve learning and memory impairments through against oxidative stress and synaptic damage, Phytomedicine. , 2017, 25:15-24.
(2)Xue-Fei Ji,Tian-Yan Chi,Qian Xu,Xiao-Lu He,Xiao-Yu Zhou,Rui Zhang, Li-Bo Zou,Xanthoceraside ameliorates mitochondrial dysfunction contributing to the improvement of learning and memory impairment in mice with intracerebroventricular injection of Aβ1-42,Evedence-based complementary and alternative medicine,Volume 2014.
(3)Xu Q,Ji XF, Chi TY, Liu P, Jin G, Chen L, Zou LB, Sigma-1 receptor in brain ischemia/reperfusion: Possible role in the NR2A-induced pathway to regulate brain-derived neurotrophic factor, J Neurol Sci. , 2017, 25:15-24.
(4)Xu Qian,Ji Xue-Fei, Chi Tian-Yan, Liu Peng, Jin Ge, Gu Shao-Li, Zou Li-Bo*, Sigma 1 receptor activation regulates brain-derived neurotrophic factor through NR2A-CaMKIV-TORC1 pathway to rescue the impairment of learning and memory induced by brain ischaemia/reperfusion, Psychopharmacology, 2015, 232: 1779-1791.
其他: